Walter Blanco, is a frustrated chemistry teacher at a high school, who after receiving an untreatable cancer diagnosis, turns to desperate measures to secure his family's financial future. Following an encounter with his brother in law - a narcotics officer with the local police - he realises the potential in cooking crystal meth, a drug that is becoming increasingly popular. With his lab expertise he can create a much better drug than what is currently on the streets. To keep his hands clean, he enlists the help of a former student, Jose, to get the drugs on the streets and make enough money quickly to give his family the security they will need after he passes away. However Walter's product is so good that it quickly disrupts the entire local drug scene and he is not able to get out as quickly as he had hoped. Instead he finds himself dragged deep, deep in to the dark world of the international cartels and gangsters who run them. Metastasis is the Colombian remake of Breaking Bad, one of the most successful and critically acclaimed television series of all time. With local nuances that add new elements to the legendary story, Metastasis ran for five hit seasons, just as the original.